Showing posts with label cold chain. Show all posts
Showing posts with label cold chain. Show all posts

Saturday, November 28, 2020

Thanking Outstanding Journalists in the Pandemic

In the pandemic, a positive feature has been the number of excellent journalists that I have had the pleasure to interact with through interviews. The writings of journalists and their investigative journalism have kept us informed as new information becomes available at, sometimes, an incredibly rapid pace. Journalists are challenged now for so many reasons, including their personal safety and I thank them for their work ethic, their outreach, and their attention to digging deep. 

Honestly, one of the highlights in this pandemic is the numerous conversations that I have had with journalists, some lasting for an hour or more. I have also very much enjoyed being interviewed for several radio programs, both in the US and in England, and have enjoyed being on TV news programs in Boston and in Dallas. The intelligence of the journalists and their thoughtful questions keep this academic intellectually engaged on many dimensions. Sometimes the interviews even end with laughter and it is clear that a real connection has been made. Also, as an educator, I believe that we can play an important role, especially if our expertise is relevant, to helping journalists and the media, in general, get the important news out in the pandemic, whether it involves, for example, product shortages due to supply chain disruptions, challenges associated with the cold chains needed for the Covid-19 vaccines, and many logistical issues surrounding the distribution of the vaccines, as well as technological innovations in the vaccine cold chain.  Recently, the professional society of INFORMS, which has over 11,000 members had its virtual conference, and I was interviewed by Glenn Wegryn on my experiences with the media in the pandemic. You can view it on youtube.

In my previous blogpost, I wrote about the vaccine cold chain and noted several informative articles, including the fascinating one by Lori Hinnant in the Associated Press on challenges of the vaccine cold chain in developing countries and even the CareTalk podcast that I was honored to be a guest on.

When responding to inquiries from journalists and the media, one has to be ready, since often (but not always), they are on a tight timeline (and this is especially evident in the pandemic). I have received quite a few messages from journalists in my email marked URGENT in the subject line.

A while back I was interviewed by Charlie Slack, for the excellent article, "The pandemic offers valuable lessons that can help you compete in the months and years ahead," for the Bank of America, which is part of a series. I also thoroughly enjoyed speaking with Jeff Reinke for his article published on manufacturing.net (which has been reprinted on other outlets), "Vaccine poses immense, unprecedented distribution challenges." Jeff's knowledge of logistics is vast - honestly, I could have spoken with him for hours!

I also very much enjoyed speaking with Michael Goldstein for his superb article in Forbes, "Covid-19 vaccines are here: Are airlines ready to transport them" which presciently anticipated the big news today about Pfizer's vaccine being air shipped from Belgium to the US yesterday via United cargo!

And, I hope that all of you who celebrated Thanksgiving had a pleasant, festive day! Just before the holiday I was contacted again by a Senior Technical Writer for USA Today, Jessica Guynn, who had interviewed me a few months ago, and her latest article on product shortages, including that of, yes, here we go again, toilet paper (if you read it to the end it may make you smile). I was laughing out loud, having been reminded of summers spent at scouting camps; sleeping in a tent, and having access to very limited shower (cold water only) and bathroom facilities (outhouses).

It was a pleasure to speak with Karen Pallarito, whose article, "This is why the COVID-19 vaccine is going to take longer than you think," published on Livestrong.com.

I would also like to thank Kim Severson, a journalist for The New York Times, who had interviewed me for an article on food, "7 ways the pandemic has changed the way that we shop for food," that was published in early September. The article was very well researched and insightful. It was special to speak with Katie Surma of The Chicago Tribune for her article, "Chicago-area grocers stock up as COVID-19 cases rise.

And, as for technological innovations, Jared S. Hopkins of The Wall Street Journal, who has been writing very timely articles on the vaccine rollout, interviewed me for an article on new vials developed by Corning, that can enhance the storage and transport of the Covid-19 vaccines.

I had mentioned earlier in this blogpost that one had to be ready to respond to media inquiries. For example, I was contacted by BBC radio recently in the early afternoon for a live segment for the Colin Murray show, which took place at 5:30ET (but 10:30PM UK time).  Since I had been a Visiting Fellow at All Souls College at the University of Oxford in England, I am quite good at parsing different British accents and our conversation, I believe, was terrific.

I would also like to single out and thank Larry Collins, another award-winning journalist with whom I have had the pleasure and honor of speaking in the pandemic for the news segment, "COVID-19 vaccine distribution, shipping present challenges." The TV news segment from Dallas can be accessed here. Larry is a fabulous interviewer!

It is important to add that not every interview that one might do results in quotes. Nevertheless, I have gotten thanks from two journalists for educating them and several have told me that they wish that they had majored in operations and logistics and college, so I consider this a success.

And for those of you who are interested in reading and learning more,  INFORMS maintains regular updates on its members on its website, who have appeared in the media, and who have been interviewed on various pandemic topics, including healthcare and supply chains. This is an excellent, very valuable service.

Wednesday, October 28, 2020

The Covid-19 Vaccine Cold Chain

On September 18, 2020 my article, "Keeping coronavirus vaccines at subzero temperatures during distribution will be hard, but likely key to ending pandemic," was published in The Conversation. I believed that it was imperative (and my Editors at The Conversation agreed) to start speaking to a broad audience on the necessity and importance of the cold chain to the effective distribution of the Covid-19 vaccines that are presently under development by major pharmaceutical firms.  There was much discussion and coverage in the press about the manufacturing aspects of the different vaccines as well as the R&D involved. However, there was very little being discussed about the distribution issues.  It was imperative to me  that emphasis (and associated challenges) on getting the approved vaccines ultimately from point A (manufacturing) to point B (point of administering of the vaccine), with the quality preserved in the transportation and distribution process, be brought to everyone's attention.

I have conducted research on perishable product supply chains from food to pharmaceuticals and even co-authored a book on the topic.

There are now 4 major Covid-19 vaccines that are far along in the trial phases and this is quite promising, with the Moderna and Pfizer vaccines requiring storage below freezing (Pfizer's to the extreme temp of -94 F) with those of Astrazeneca's and John & Johnson's needing to be in the range of 2-8 degrees C, which is standard for many vaccines. 

I have published multiple articles in The Conversation, but this one generated the greatest number of comments and even emails to me from around the globe, which continue. Clearly, the article that I wrote had touched on a very important issue, and I am also grateful that the article got reprinted in multiple media outlets.

Since the publication of my article, much has happened, and the momentum keeps on growing.

I had the pleasure of being interviewed by David Williams and John Driscoll for their Care Talk podcast, the link to which is below. 

 

Lori Hinnant, who is an Associated Press journalist, based in Paris, subsequently interviewed me for a fabulous article, "Vaccine storage issues could leave 3B without access."  My colleague at the Carey School of Business at Johns Hopkins, Tinglong Dai, was also interviewed for this article, which has been reprinted internationally in numerous outlets and also published in The Washington Post and ABCNews.


I have had additional interviews with journalists at The Wall Street Journal and am quoted in the article, "Covid-19 vaccines to be stored secretly under tight security," by Jared S. Hopkins on the security of the distribution of the vaccine. There is a slightly modified title in the hard copy version - a colleague kindly delivered his copy to my door!

I've done research with collaborators on freight security of highly value cargo and clearly the Covid-19 vaccines fall into this category!

And, on November 6, I will be featured on the NPR show The Pulse, based on an interview on the vaccine cold chain conducted by Alan Yu.

One of the goals of my Conversation article was to make the cold chain distribution issues more visible in order that appropriate preparedness measures would be taken, both nationally and globally, so that, once vaccines are approved, time is not wasted and the vaccines do not go to waste as well.

Many thanks to all those who have responded, including the amazing journalists, who continue to keep this important topic in the news!

And, just before publishing this blogpost, I received another inquiry from a journalist requesting an interview because of my article in The Conversation!


Tuesday, June 16, 2020

Postscript on My INFORMS Webinar: Blood, Sweat, and PPEs: Rescuing Perishable Product Supply Chains and Impacting Policy Through Analytics

First, I would like to thank the INFORMS Practice Section for the invitation to deliver the inaugural webinar in its Analytics Series, which took place last Friday. The title of my webinar was: "Blood, Sweat, and PPEs: Rescuing Perishable Product Supply Chains and Impacting Policy Through Analytics." 

As noted on the INFORMS Section's webpage: the goal of the webinar series is to bring awareness of the value of applying analytics to real-world problems. The series is organized by Dr. Patricia Neri of Bayer Crop Science and Dr. Carrie Beam of the University of Arkansas.


Also, special thanks to all those who were able to join in. I was thrilled to hear from colleagues in many different countries, who were able to Zoom in.

This blogpost is a postscript on the webinar with links to my presentation and to the full webinar, which is now on youtube, and answers to questions in the Q&A.

That morning began with getting ready for the virtual event.

The logistics of the webinar, which was carried out via Zoom, was handled by Beth West and Mary Leszczynski of INFORMS and it was exciting to have it be open to the public and to have the registration be free. 

We had had multiple practice sessions, since there were slides to be included prior to my presentation about the series as well as slides afterwards, providing a link to this blog and noting that the webinar would also be posted on youtube.

Dr. Neri gave a lovely introduction to my presentation.
In the webinar, I spoke about a variety of perishable product supply chains impacted by the Covid-19 pandemic, including: food, PPE, and blood supply chains, and also provided some hope based on convalescent plasma as a treatment, under the reality of competition.  I discussed both earlier relevant research as well as research that we have conducted on supply chain disruptions and resilience during the Covid-19 pandemic. And, I also spoke about the impact of analytics during the Covid-19 pandemic on policy, including our work on blood supply chains. I emphasized the importance of the work being done by our Operations Research and Analytics community and also highlighted inspiring younger generations.



The webinar is now also online, thanks to INFORMS. 



Dr. Carrie Beam expertly handled the Q&A.

And, as promised, since we did not get a chance to address all the questions, below I provide a list of questions, followed by my response. For completeness, I also include the questions that were "live."


Question from Don Mustard of Canada: Covid has exposed a global supply chain that was not prepared for a global pandemic. What is the role of government in reinforcing supply chains' structure against disaster, ensuring that disruption is minimized?

My answer: This is an excellent question. I believe that national governments must be involved in disaster mitigation and preparedness and clearly this pandemic is a healthcare disaster. First and foremost, the government must ensure that we are prepared for a worst case scenario, as we are are experiencing now. This is an extreme disaster given the impact and prevalence over space and time (unlike an earthquake, flood, tsunami, etc.).  Many of the supply chains that have been most severely disrupted now are being referred to as "critical infrastructure" and the associated workers are truly essential ones. The government should guarantee that we have adequate stockpiles of  PPEs and medical supplies as well as the capacity to produce them, including vaccines. Investing in food supply chains is also warranted. As I discussed in my presentation, labor in many industries, including food processing, has suffered in the pandemic, resulting in product shortages. Having healthcare for workers will keep everyone safer and make our supply chains more resilient.

Question from Dr. Angelika Leskovskaya of Southern Methodist University: Will it be possible to send slides and probably recording after the webinar?

My answer: The links to the slide and the recording of the webinar are given above. I will check with INFORMS about further broadcasting of the information. Thank you.

Question from Don Mustard of Canada: Perhaps could you discuss your thoughts on the concept that Covid didn't create problems in the supply chain, but rather, just exposed them... and what your confidence that we will learn from this (vs. revert to our historical patterns of behavior).

My answer: Clearly, the pandemic dramatically illustrated to everyone not only the importance of supply chains but also the need for flexibility, agility, and having multiple suppliers, among many other important characteristics. At the same time, the necessity of closing many businesses,  incorporating social distancing measures in production and processing facilities, dealing with employee illnesses and fears of contagion, modifying freight service provision, etc., put many additional stressors on the supply chains. I do believe that Operations Research and Analytics will be utilized and valued more by many organizations as a result of the pandemic because our tools are extremely useful and can identify vulnerabilities (as well as synergies) in supply chain networks. We (firms, organizations, governments) cannot turn our backs on the lessons learned.

Question from Dr. Duncan Klett, Cofounder of Kinaxis: It seems logical that national stockpiles should be filled to close to necessary levels, then supplies would flow through the stockpile so the oldest get sent out to hospitals for immediate use, keeping the stockpile "current."

My answer: Yes, one would think that that would be and should be the case. I believe that some were surprised that masks actually can, in effect, perish over time because their quality deteriorates. This should have been addressed and mitigated way before the pandemic hit us.  

Question from Dr. Amir Masoumi of Manhattan College: Once the volume of blood donations and transfusions across the US are back to "normal", in which direction do you see the blood banking industry moving with respect to balancing the supply and demand for blood products?

My answer: I believe that there will have to be more cooperation, rather than competition among blood service organizations. That was actually one of the themes in a paper co-authored with you and with Dr. Min Yu that I mentioned in my webinar presentation. Also, with the demand for convalescent plasma, obtained through apheresis of blood donations, as I had discussed in my presentation, which is emerging as a possible treatment for Covid-19, there is now some added hope for hospitalized patients battling this disease. There is competition now for the valuable convalescent plasma but, ultimately, there should be system optimization and allocation accordingly.


Question from Rishabh Bhandawat, PhD Candidate at the University of Buffalo: Would centralized inventory with some sort of sharing mechanism have helped with Covid? 

Answer: I think that definitely, yes, especially in the case of the National Stockpile of PPEs and medical supplies. However, as I had mentioned in the webinar, there were not sufficient amounts plus there was deterioration in the quality (hence, perishability) of many items, which exacerbated the shortages. We need a sufficient centralized inventory and management of the critical needs supplies along with a fair distribution to points of demand.

Question from Dr. Robin Lougee of IBM: Does Anna want to talk about the role of blockchain?

Answer: Time did not permit a discussion on blockchain.  However, how blockchain can influence supply chains in the pandemic would be an excellent topic for a future webinar. Thanks.

Question from Dr. Robin Lougee of IBM: What's the NEXT presentation in the series?

Answer: The next webinar will take place on July 10, 2020 and is entitled, "Inventory, Packages, Price Points and People: An Inside Look at leading Technical People." The webinar will consist of panelists who will address: "How do the best geeks in the industry motivate and manage their technical teams. The panelists will be: Dr. Pooja Dewan of Otis Elevator, Dr. Anne Robinson of Kinaxis, Dr. Mallory Freeman of UPS, and Dr. Pallav Chhaochhria of Citi.

Many thanks for all the great questions! During the Q&A there were also comments sent by Marino Biagini and by Teja Krasek (from Slovenia), which were very much appreciated.

There was a glitch at the beginning of the webinar, which was quickly corrected, by the projector unmuting the computer. The Chat facility was disabled by the INFORMS folks due to prior issues for security reasons. 

Being "first" in anything is always risky, but nothing ventured, nothing gained. And with technology and the Internet there is always the possibility of a disruption.

I like forward to further discussions and important contributions from our community during these challenging times and when the pandemic is past us.

Wednesday, April 4, 2018

Meningitis on Campus - An Extremely Timely Lecture by a Public Health Nurse Extraordinaire

Yesterday was the final guest lecture in my Humanitarian Logistics and Healthcare class this semester at the Isenberg School and it was extremely timely and interesting.

The students and I had the privilege of hearing from Ms. Ann Becker, who is the University Health Services (UHS) Public Health Nurse and the Unit Coordinator for the Medical Reserve Corps at  UMass Amherst.
The title of her guest lecture was: Meningitis on Campus - Reaching Students During a Meningitis-B Outbreak.

As some of you may have heard, this past Fall there were two cases of Meningits-B, one in late October, and the other three weeks after. Since no linkages between the two cases could be identified, the Centers for Disease Control (CDC) termed these cases an outbreak. Students get vaccinated for other strains regularly but not for the B strain. And, in early March, the CDC confirmed that another case was diagnosed in a Smith College student, so this is now a 5 College outbreak. 

This disease is very rare but it can progress rapidly with extremely dire effects.  I remember last semester when I was teaching my Transportation and Logistics class at the Isenberg School that one of the students in this class knew the first student to contract meningitis-B because they were both in the same fraternity, and he was involved in helping to raise funds for the student's care and recovery.

10-40% of 16-24 year olds are carriers of this bacteria, and the illness is transmitted through direct contact with secretions. Risk factors include large parties and sharing of drinks, cigarettes, etc., and being stressed and not sleeping enough only increases the probability of contagion. It takes at least a week to identify the meningitis strain from a culture and these were sent both to the Massachusetts DPH and the CDC.

The UMass Amherst campus responded extremely professionally. There had actually been simulation exercises in place for a mass vaccination and I had even blogged about this. This was inspired by the cases in the US a few years back on college campuses, including Princeton University. And, at that time, there was not even a vaccine available in the US (but was in Europe). 

The UMass Amherst campus responded with an emergency call center, since, once the news went out, the staff was inundated with calls. Staffing was identified for the initial vaccination clinics and vaccine supply and cold storage had to be managed. It was interesting to hear that the annual flu clinics also served as a prep for the mass vaccination clinics. UMass Amherst, as a university, is in the business of education, and it was essential to have no disruptions to courses. The healthcare staff, with assistance from nursing students and the Medical Reserve Corp, in 3 hours gave 700 vaccinations. "Being prepared and knowing people" helped in the efficiency of the processes as well as their effectiveness. The cost for 10,000 doses was $1.5 million from Glaxo Smith.

In order to reach students, there were numerous communication media that were utilized - from social media and emails to the notification of parents and having a dedicated strip banner with info on the UMass homepage. Also, the MA DPH sent out messages to every healthcare provider in the state. Two shots are required for the vaccine and there was a one week Thanksgiving break in late November with some students also getting their first vaccines from their home healthcare providers.

UMass Amherst had 4 walkin clinics over consecutive days from noon until 6PM and Ms. Becker showed the class an excellent diagram with the flow of the process, which is something all the Operations students enjoyed and appreciated. It began with the registration and asking for the insurance (if students or insurers could not pay, then (bravo) UMass Amherst covered the expense). Impressively, the number vaccinated reached 1,500 per day with the longest wait time of 20 minutes, which is not bad, given the volume of students as well as the severity of the disease.

It was interesting to hear that the processes were aided by the youth of those vaccinated and that they were all ambulatory.
There are still unknowns, however, since we don't have an accurate count of how many students have received the two shots that are needed, as Ms. Becker pointed out in her lecture.  Interestingly, she also mentioned that, after a year of no more outbreaks, can we be considered "in the clear." They do know that more than 3,000 + students have already had 2 shots.

Our University Health Services are continuing with walk-in clinics, which is great and also reassuring, and they have also done an amazing job in educating students as to proper behavior so that this bacteria does not spread.

We presented our fabulous guest lecturer with a certificate and a gift from the Isenberg School and took the group photo below as a memento.

And, in her last slide of her presentation, featured above, we can see our Chancellor, Dr. Kumble Subbaswamy, "saying": Get Vaccinated.

It was very special to have Ms. Becker speak to my class and her expertise and kindness are truly inspiring. We are very lucky to have her at UHS at UMass Amherst!