Sunday, June 22, 2014
Delay Tolerant Networks - When Transportation Trumps the Internet
Being based in Europe for a couple of glorious weeks allows for some great conference chaining which I have been doing and have also been highlighting on this blog in several previous posts.
There has also been a North South theme to this visit since I have given talks at workshops and conferences, since my arrival, in Erice, Sicily (south), came back to Sweden (north), then ventured to Taormina, Sicily and Catania, also in Sicily (south) and onwards to Chalkidiki, Greece (south). Back in the north now in Gothenburg.
As a researcher and a very frequent flier, who also works on networks and their numerous and fascinating applications, including transportation and communications, practical, real-world experiences reinforce my research and vice versa! Plus, you acquire great stories to share with your students in classes.
Before flying to Europe, we were finishing up a paper on Delay Tolerant Networks, and, in the meantime, we have also completed another one. This is a collaboration initiated by a doctoral student in engineering, who is from Colombia, and who is visiting my Co-PI on our National Science Foundation project, Network Innovation Through Choice, Professor Tilman Wolf of the College of Engineering at UMass Amherst. The doctoral student is Luis Marentes and he sat in on my SOM 825 course this past semester on Variational Inequalities, Networks, and Game Theory.
In the beautiful parts of southern Europe - I can't resist sharing some photos of Sicily and Greece where I spoke at below, there, nevertheless, were major issues with the Internet! Even when it was up it might take as long as an hour to access an email message and, as for tweeting 140 characters, sometimes we waited for 24 hours, and the tweet was still not transferred. But we were patient and the beauty and the caliber of the conferences and people made up for the technology shortcomings. I will share a story at the end of this post.
Our work on Delay Tolerant Networks, is inspired, in part, by that of Dr. Alex "Sandy" Pentland of MIT, whom we have hosted at the Isenberg School of Management at UMass in our INFORMS Speaker Series, and whom I have interacted with on other occasions. I am a huge fan of Sandy's and was thrilled when he was ecleted to the National Academy of Engineering this year.
Pentland's paper, DakNet: Rethinking Connectivity in Developing Nations, published in Computer in 2004, speaks of connecting remote villages in India and Cambodia through a combination of wireless and asynchronous means.
When I tell people that there are parts of the globe in which residents desperately need information that we take for granted and that which we access through the Internet but they lack digital connectivity because of market and pricing forces (including poverty) and can benefit from using transportation modes (from busses to mules - I am not kidding) to secure the information, I receive expressions of shock!
In our first paper, "Overcoming Economic Challenges of Internet Operators in Low Income Regions Through a Delay Tolerant Architecture with Mechanic Backhauls," Luis Marentes, Tilman Wolf, Anna Nagurney, Yezid Donosoa, and Harold Castro, we study the following. Regions with low population densities and low income, which may be rural, are far behind in Internet access as compared to their urban counterparts. Economic unsustainable deployments have been suggested as one of the factors with high negative impact. Researchers using the Delay Tolerant Network Architecture (DTN) have established a less expensive alternative, but they do not provide guidelines on how to price the new possible services nor any indication as to operators’ profitability. These two points are the contributions of this paper. Based on a continuous pricing model, we show that projects using the DTN architecture have a positive net present value using real demand data.
In this paper, we also explore how far the use of this technology is going to help in attaining profitable deployments with real and delay tolerant services. Our findings indicate that although it is not possible to support the investment reported in a previous actual deployment, a great portion of the investment is actually covered by the predicted gross profit of our model. We hypothesize that the remaining value is affordable if service differentiation is enabled by means of a new architecture. Three components to test the hypothesis are introduced: (1) the pricing elements to form service level agreements, (2) a general overview of the architecture requirements, and (3) a novel pricing model. In this regard, our results show a positive effect of service differentiation which improves profits by 10% without any customer additional payment.
In our second paper, "Towards Pricing Mechanisms for Delay Tolerant Services," Luis Marentes, Tilman Wolf, Anna Nagurney, and Yezid Donoso, we again note that one of the applications of the Delay Tolerant Architecture (DTN) is rural networks. For this application researchers have argued benefits on lowering costs and overcoming challenging conditions under which, for instance, protocols such as TCP/IP cannot work because their underlying requisites are not satisfied. New responses are required in order to understand the true adoption opportunities of this technology. Constraints in service level agreements and viable alternative pricing schemes are some of the new issues that arise as a consequence of the particular operation mode.
In this paper, we propose a novel model for pricing delay tolerant services, which adjusts prices to demand variability subject to constraints imposed by the DTN operation. With this model we also show how important parameters such as channel rental costs, cycle times of providers, and market sensitivities affect business opportunities of operators.
In both of these papers, the consumers respond to the average time of the delivery of the services, which could consist of a combination of communication and transport modes!
As for our journeys in southern Europe, we ended up, in Chalkidiki, Greece taking the ferry to the neighboring town of Marmara (transport) and back to seek a decent WiFi connection.
And we were successful. Decent WiFi was found at a restaurant at which we also had a fabulous meal - it was so good that I blew kisses to the cooks and then they surprised us with a tray of fresh cherries and exotic, delicious Greek desserts!
We then, the next day, explored another mode of transport to access the Internet - we walked rather than taking the ferry to Marmara and it took us about the same amount of time - plus the beach views were glorious. And for those news junkies there, we even found a small shop where we purchased the same day edition of The International New York Times, which was printed in Greece. The owner is British.
Thursday, August 18, 2011
Higher Quality at Lower Prices -- An Agreement for Generic Medicines that Must be Passed
In terms of healthcare, the leading work of our colleague, Professor Ed Kaplan at the Yale School of Management, in needle exchange programs to reduce AIDS, immediately comes to mind.
When it comes to healthcare, some of the major issues that we are faced with in our country today are twofold: high costs and (low) quality, with an associated component being questionable availability whether of healthcare providers or even medicines or service, in general.
Healthcare is so important that the only way in which we may be able to guarantee change is through legislation. During times such as these, when our medical nuclear supply chains have exhibited shortages of critical diagnostic radioisotopes, and when cancer drugs cannot be obtained by patients who need them for their survival, we are clearly in a medical crisis.
We wrote the OpEd piece: Viewpoint: Passage of American Medical Isotope Production Act of 2011 will help ensure U.S. nuclear medicine supply chain, and today's editorial in The New York Times: A Deal to Get Cheaper and Safer Drugs argues that lawmakers must quickly approve legislation that would ensure fees from generic drug manufacturers that would enable regular inspections of out of country manufacturing plants to ensure safety, and let's not forget about availability, as I have written about passionately on this blog.
The understanding of our complex global healthcare supply chains, and associated policy making, must be based on rigorous mathematical modeling and analysis that capture the network economics aspects as well as multicriteria decision-making to ensure quality but at reasonable cost. Operations researchers, with their multidisciplinary training, as well as mindsets, and collaborative networks, are leading the way.
It is imperative, however, that we, as researchers, educators and members of professional societies, get the news out about research that can make a difference.
Some of our relevant research on multitiered, multicriteria supply chain networks:
Supply Chain Outsourcing Under Exchange Rate Risk and Competition
Zugang Liu and Anna Nagurney, Omega 39: (2011) pp 539-549.
Global Supply Chain Network Dynamics with Multicriteria Decision-Making Under Risk and Uncertainty
Anna Nagurney and Dmytro Matsypura, Transportation Research E 41: (2005) pp 585-612.
Multitiered Supply Chain Networks: Multicriteria Decision–Making under Uncertainty
June Dong, Ding Zhang, Hong Yan, and Anna Nagurney, Annals of Operations Research 135: (2005) pp 155-178.
Some of our research on healthcare supply chains, specifically:
Medical Nuclear Supply Chain Design: A Tractable Network Model and Computational ApproachAnna Nagurney and Ladimer S. Nagurney (2011)
Multiproduct Humanitarian Healthcare Supply Chains: A Network Modeling and Computational Framework
Anna Nagurney, Min Yu, and Qiang Qiang (2011)
Supply Chain Network Operations Management of a Blood Banking System with Cost and Risk Minimization
Anna Nagurney, Amir H. Masoumi, and Min Yu, Computational Management Science: (2011), in press
Supply Chain Network Design of a Sustainable Blood Banking System
Anna Nagurney and Amir H. Masoumi, in Sustainable Supply Chains: Models, Methods and Public Policy Implications, T. Boone, V. Jayaraman, and R. Ganeshan, Editors, Springer, London, England, 2011, in press.
Friday, April 2, 2010
From the NCAA Tournament to Pediatric Vaccines
His presentation, An Analysis of Pediatric Vaccine Pricing and Stockpiling Issues, was simply outstanding! He recently returned from a trip that took him to Australia and Japan to investigate different vaccine issues in those countries. He discussed how integer programming can be used in the pricing of vaccines with real-world data and how he used stochastic programming to formulate and answer questions regarding the stockpiling of vaccines. He informed the audience of the challenges that vaccine manufacturers are faced with. He told the students to be willing to do "work for free" because sometimes great opportunities arise from doing research that helps others (as he had experienced with a pharmaceutical company and CDC project).
Today, as well, Dr. Jacobson was one of nine experts whose commentary appeared in The New York Times "Room for Debate" on the theme, How to Improve the N.C.A.A. Tournament! It was very cool to see Dr. Jacobson on the same short list as the Women's Basketball Hall of Fame member, Rebecca Lobo Rishin, and the former Temple University men's basketball coach, John Chaney, among other sports experts! Actually, they are lucky to be on the same short list as Professor Jacobson!
Now you might be thinking how can someone be an expert on healthcare topics such as vaccine production, stockpiling, and pricing, coupled with the analysis of sports tournament outcomes?! Dr. Jacobson is also an expert on aviation security and was a Guggenheim Fellow in 2003. His degrees are in mathematics and operations research (with a PhD in the latter from Cornell University). Having critical analytical skills, a strong math background, and the ability to develop creative and insightful mathematical models, with important policy implications, can lead you to study and address numerous important problems.
Dr. Jacobson is a Renaissance man and we are so grateful that he took the time out of his extremely busy professional schedule to come and speak at the Isenberg School of Management at UMass Amherst.
We also thank Barry List of INFORMS and its Speaker Program for co-sponsoring Dr. Jacobson's wonderful talk today!
Friday, March 26, 2010
Lecture on Pediatric Vaccine -- Pricing and Stockpiling Issues
I have heard Dr. Jacobson speak (last time was at the INORMS Conference in Puerto Rico) and he is a fantastic speaker plus his research is always on timely topics and it attracts a lot of media attention because he has very creative approaches to identifying problems and solving them.
Biography: Sheldon H. Jacobson is a Professor and Director of the Simulation and Optimization Laboratory in the Department of Computer Science at the University of Illinois. He has a B.Sc. and M.Sc. (both in Mathematics) from McGill University, and a M.S. and Ph.D. (both in Operations Research) from Cornell University. His methodological research interests include the stochastic analysis and design of heuristics for intractable discrete optimization problems, and the analysis of stochastic dynamic assignment problems. His applied research interests address problems in the areas of homeland security (aviation security) and health-care delivery systems (public health: immunization and obesity). His research has been recognized with several awards, including the Aviation Security Research Award by Aviation Security International, the International Air Transport Association, and the Airports Council International (in 2002), a Guggenheim Fellowship (in 2003), and the Institute of Industrial Engineers Outstanding Paper Award (in 2009). His research has been published in a wide spectrum of journals, and he has received research funding from several government agencies and industrial.
PRESENTATION TITLE: An Analysis of Pediatric Vaccine Pricing and Stockpiling Issues
Abstract: The United States Recommended Childhood Immunization Schedule outlines a comprehensive schedule of vaccines and vaccination periods to protect each newborn infant from several diseases that once plagued children. This presentation covers two important issues related to pediatric vaccines and immunization: pricing of new combination vaccines and pediatric vaccine stockpiling. Results are reported on using integer programming models to analyze the price and market value of two partially overlapping pentavalent combination vaccines for pediatric immunization. Results are also reported on using a stochastic inventory model to assess the impact of pediatric vaccine stockpile levels on immunization coverage. The implications of these issues on pandemic influenza vaccine manufacturing and distribution are also discussed.
Date: Friday, April 2, 2010
Time: 11:00AM - Noon
Place: Isenberg School of Management Room 112
UMass Amherst
The announcement for this talk can be found at:
http://supernet.som.umass.edu/informs/speakernew.html